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Vaginal Progesterone Is Equally Effective In Achieving Pregnancy Outcomes As Injectable Progesterone In Donor Egg Cycles

November 8th, 2008 · No Comments
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“We found no consequential difference contained via pregnancy conclusion linking patients treat adjacent to vaginal progesterone versus progesterone administered intramuscularly,” said Dr. Berger. “Further, vaginal progesterone enjoy the added power of excuse sore intramuscular immunisation.” In 225 egg contributor cycle, 105 patients received vaginally-administered progesterone (CRINONE® 8% (a bioadhesive progesterone gel)) and 120 received IM progesterone. The implantation rate be 43.8% in favour of vaginal progesterone versus 37.1% for IM progesterone (p=0.175). Recipients treated with vaginal progesterone get done a 58.1% pregnancy rate and a 51.4% nativity rate, versus a 53.3% pregnancy rate (p=0.503) and a 48.3% delivery rate (p=0.689) for patients acceptance IM progesterone. The pregnancy lesion rate was 10.5% for patients using vaginal progesterone and 10.8% for IM progesterone user (p=1.00).

“This workroom rationally identify that vaginal progesterone gel achieve the same pregnancy outcomes by means of progesterone administered via an intramuscular injection. This be essential substantiation that CRINONE® 8% extend patients an efficacious and more handy select for providing progesterone espouse in barrenness remedy,” Berger added.

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About the Institute for Reproductive Health The Institute for Reproductive Health is dyed-in-the-wool to helping women and men breed informed judgment roughly family planning and providing them subsequent to undressed and effective instinctive option. As subdivision of Georgetown University’s Department of Obstetrics and Gynecology, the Institute conduct research to whet natural methods of family planning and testing them in resource delivery settings.

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